Did You Know!

Losing Teeth Too Early Can Actually Be a Sign of a Bone Disorder

A little-known genetic condition called hypophosphatasia (HPP) can weaken bones and cause unexpected dental problems.

People with this disorder have difficulty properly mineralizing their bones and teeth because of reduced activity of an enzyme called alkaline phosphatase.

One of its most surprising warning signs is losing baby teeth unusually early, sometimes with their roots still intact.

In adults, the condition can cause recurring foot fractures, thigh bone fractures, chronic bone pain, and premature loss of permanent teeth.

Because symptoms can resemble osteoporosis or other common conditions, hypophosphatasia sometimes goes unrecognized for years.

Interesting fact: A persistently low alkaline phosphatase level on a routine blood test can be an important clue that prompts doctors to investigate this rare disorder.