Did You Know!

Some People Have a Disorder That Makes Their Muscles Turn Into Bone

Disorder: Fibrodysplasia Ossificans Progressiva (FOP)

This extremely rare genetic disorder causes soft tissues, including muscles, tendons, and ligaments, to gradually develop bone where bone shouldn’t exist.

  • Minor injuries, falls, or even certain medical injections can trigger painful episodes of new bone formation.
  • The extra bone can permanently restrict movement and lock joints into place.
  • FOP is estimated to affect approximately 1 in 1 million people worldwide.

Surprising fact: People with FOP are often born with unusually shaped big toes, which can provide an important early clue to the condition.